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Whether it’s exploring Argentina’s colourful capital, tasting wines in the Mendoza wine region, or trekking through Patagonia’s Lake District, travelling between Santiago and Buenos Aires will deliver adventure, culture, and fun.

Our Santiago to Buenos Aires Tours

Map of Trek Patagonia including Argentina and Chile

Trek Patagonia
10 Days From 3760

Visit South America and travel to Patagonia to experience the 'W' Trek in Torres del...

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Map of Best of Chile & Argentina including Argentina and Chile

Best of Chile & Argentina
8 Days From 2585

Embark on an unforgettable journey through the amazing landscapes and captivating...

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Map of Chile & Argentina Real Food Adventure including Argentina and Chile

Chile & Argentina Real Food Adventure
11 Days From 3130

Taste South America's splendour of Chile and Argentina, passing through Chile's wine...

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Map of Patagonia Explored including Argentina and Chile

Patagonia Explored
14 Days From 4535

Travel from Chile to Argentina through the Patagonia region, stopping at Santiago,...

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Tailor-Made trips

Take two or more on an exclusive trip and tailor your itinerary

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Santiago to Buenos Aires Tours Reviews

Read more about South America

Mar 29, 2018

Why you should visit Patagonia’s Perito Moreno...

Reading Time: 5 minutes All I could muster was a smile that enveloped my entire...

Jan 08, 2018

Meat lover? These 6 destinations are a must-visit

Reading Time: 10 minutes For those carnivores on the hunt for their next meat...

Mar 14, 2018

What to pack for a trip to Patagonia

Reading Time: 6 minutes You can get back to planning hikes and the perfect...

Jan 31, 2018

Everything you need to do, see, eat and drink...

Reading Time: 5 minutes In the neighborhood of San Telmo, cobbled streets lead...

Jul 18, 2019

8 awesome experiences you MUST have in Argentina

Reading Time: 5 minutes No matter what kind of traveller you are – foodie, wine...