1. New York
You can be anyone you want to be in NYC. Indulge your artistic side at MoMA, mingle with the Gordon Geckos on Wall Street, cheer like a pro at a Yankees game or kick back at a bar with a Manhattan and a new pair of Jimmy Choos.
2. San Francisco
San Francisco is made of sunshine, seafood and a whole lot of hills. This is the place to embrace your inner (or outer) bohemian. But it's not all 'flowers in your hair' and free thinking, be sure to take a ferry to Alcatraz and scoff down a clam chowder at Fisherman's Wharf.
3. New Orleans
The Caribbean meets France and Africa in New Orleans. Music is everywhere, and so are the friendly faces. The city comes to life after dark so have an afternoon nap, get some comfortable shoes on and get ready to bar hop the night away.
4. Las Vegas
Hello Lady Luck! Days somehow disappear in the hedonistic blitz of color, light, showgirls, casinos and offers too good to refuse. Try to escape the endless buffets to catch a real Las Vegas show; there's everything from death-defying acrobats to Elvis on offer.
5. Chicago
The financial and political powerhouse of Chicago has been the home of two of the most influential people in the world - President Obama and Oprah. Famed for its distinctive architecture, booming performing arts scene and sports-mad locals, the 'Windy City' shouldn't be missed.
6. Miami
The air is warmer, the clothes smaller and the colors are somehow brighter in Miami. Jewish, Latin and Caribbean cultures blend to make a heady mix of great food, even better music and a nightlife filled with the spirit of fiesta. Hang out on perfect beaches, spot classic cars and gaze at the beautiful people as they strut their stuff.
7. Los Angeles
Search beyond the stardust of Hollywood and the excessive price tags of Rodeo Drive, to find the true essence of Los Angeles. Home to a melting pot of cultures, uber-cool restaurants, a hip art scene and the eclectic vibe of Venice Beach, LA is so hot right now!
8. Seattle
The birthplace of grunge music and iconic super-companies like Microsoft, Boeing and Starbucks, Seattle offers so much more than great coffee. Markets packed with fresh produce, a harbor perfect for boating, vibrant public art and a thriving live music scene combine to make Seattle a must-see city.
9. Memphis
History comes alive in the heritage-filled streets of Memphis. Whether it's at Elvis Presley's Graceland, the lively blues clubs and restaurants of Beale Street or the moving Civil Rights Movement Museum, it could be said that the soul of America lives in Memphis.
10. Boston
One of America's oldest cities, Boston is evolving. Working class neighborhoods are being gentrified, the industry is giving way to tech start-ups and modern architectural treasures sit alongside brown-stone buildings. Despite the change, get chatting to locals about the Red Sox and you'll soon find you're definitely in Boston.