Visit Chile, Argentina and Bolivia on a tour from Santiago to La Paz.

Travel to South America and set off on an unforgettable adventure through the soaring Andes, meeting friendly locals and discovering the rich culture and breathtaking scenery of this remarkable region. Starting in Chile's vibrant Santiago, this incredible journey continues through Argentina's picturesque wine region and includes an estancia stay – the perfect opportunity to unleash that inner gaucho. Discover the delights of colonial Salta before crossing into Bolivia to admire the mesmerising salt flats of Salar de Uyuni and fiery-red Laguna Colorada before finishing the adventure in colourful La Paz. This amazing trip is the perfect way to experience the best of this spectacular region.

Santiago, Chile
La Paz, Bolivia
Physical rating
Cultural rating
Min 18
Group size
Min 4, Max 22
Carbon offset
606kg pp per trip


  • Explore Chile's cosmopolitan Santiago
  • Visit Argentina and chill out in beautiful Mendoza
  • Tuck into a barbecue feast on a cattle ranch
  • Sip Argentine wine in Cafayate
  • Admire the colonial architecture of Salta
  • Be amazed by Bolivia's Salar de Uyuni
  • Learn about mining in Potosi
  • Keep up with the bustle of La Paz


Vibrant, cosmopolitan and chic – a stroll around Santiago is a great place to get your South American bearings. Perhaps head to the parks and shops scattered around central Plaza de Armas, or mosey through Santiago's 'Paris quarter', Barrio Bellavista.
Kick back in the laidback epicentre of Argentina's wine country, Mendoza. Get the adrenaline pumping whitewater rafting or mountain biking, or pamper the palate with some regional malbec blends at any of the numerous parkside bars and cafes.
Experience Argentine hospitality and ranch life first-hand on a working cattle station farm-stay. Explore the Pampas on horseback before savouring the mouth-watering aromas and succulent flavours of a traditional asado barbecue.
Visit the ruins of Quilmes, the ancient city of a tribe that successively staved off both the Incas and the Spanish for centuries. Wander through the haunting crumbling structures for a glimpse of the city as it once would have stood.
Learn about local wine production on a guided tour of some of South America's premier vineyards, taking the opportunity to sample some of the region's renowned drops. Wine aficionados unconfined by convention can also try out the city's red and white wine ice creams.
Delight in the laidback atmosphere and elegant colonial architecture of Salta, one of Argentina's most attractive cities. Pick a perch at one of the plaza cafes for some people-watching, thump along to the pumping local nightlife, or prowl the numerous art galleries and exhibitions.
Cross the Argentinian border into Chile's desert oasis town of San Pedro de Atacama. Take in the changing colours of the surreal natural landscapes on a sunset excursion to Moon Valley.
Make tracks for Uyuni, deep in the barren wilderness of the Bolivian Antiplano. It's some long and rough travel on these days, but the exquisite beauty of Laguna Colorado and Verde along the way more than compensate for it.
Head out on a jeep tour of Bolivia's famed salt plains for some unbelievable views and photo opportunities. During the dry season the flats are an endless expanse of white crystals, while come the rains a thin layer of clear water reflects the sky into one seamless horizon – either way, the whole thing looks like the background of a Dali painting.
Soak up the stark and subdued tones of the Andean landscapes en route to the winding narrow alleyways and majestic cathedrals of Potosi. For a total change of scene, enter the underworld – literally – for a sobering glimpse into the working conditions of Bolivian silver miners.
Wander through the charms, amulets and fetishes – at times wonderful, but always weird – of La Paz's Witches' Market. Perhaps take on the world's most dangerous road by mountain bike, or pop into the coca museum for insights into this proverbial plant's history. Celebrate an amazing journey through some of South America's most spectacular countries with a final group dinner.
View trip notes to read full itinerary


Jeep, Overland vehicle
Bush camp (no facilities) (1 night), Camping (with facilities) (5 nights), Hostel (2 nights), Hotel (12 nights)
Included activities
  • Jeep tour of Uyuni Salt Flats
  • Quilmes Ruins
  • Valle de la Luna Excursion
  • Vineyard Tour


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Important notes

1. This trip is run by our experienced overland partner Dragoman.
2. Please note that this trip requires minimum numbers to depart, and may be cancelled up until 56 days prior to departure. The places showing on the dates and availability page are an indication only so please contact Intrepid to check if your preferred date will depart before making any final arrangements, such as booking non-changeable flights.

Trip notes

Want an in-depth insight into this trip? Your trip notes provide a detailed itinerary, visa info, how to get to your hotel, what’s included - pretty much everything you need to know about this adventure and more.

View trip notes


Our Santiago to La Paz trips score an average of 5 out of 5 based on 1 reviews in the last year.

Santiago to La Paz , March 2015