Mexico City to Panama City Itinerary

Jump onboard this exciting Central American trip that takes you from the vibrancy of Mexico City through the hearts of Mexico, Belize, Guatemala, El Salvador, Honduras, Nicaragua, Costa Rica and on to Panama.

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    • QDOYC
    • Trip Price tool tip
      USD $4,065
      CAD $4,405
      AUD $4,320
      EUR €2,975
      GBP £2,400
      NZD $4,825
      ZAR R43,225
      CHF FR3,595
    • Kitty tool tip
      USD $1,250
      Extras tool tip
      USD $50 Honduras airport tax
    • Total price tool tip
      USD $4,065
      CAD $4,405
      AUD $4,320
      EUR €2,975
      GBP £2,400
      NZD $4,825
      ZAR R43,225
      CHF FR3,595
      *
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    • Overland
    • Basix
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‡ As our kitty is flexible the indicated amount is indicative only - please click here to view the kitty amount for your departure date.
Colourful textiles

Palenque, Mexico

Chichen Itza, Mexico

Carpet seller, Oaxaca

Colours of San Cristobal de las Casas

Iguana, Tulum

Day 1 Mexico

Spend time exploring the sights and sounds of intriguing Mexico City. Perhaps check out the pyramids of Teotihuacan or get out among the city’s vibrant nightlife.
ACCOM: Hotel - 1

Days 2-3 Oaxaca

Enjoy staying at a traditional posada. Take a look around the resplendent colonial city of Oaxaca before taking a guided tour around the Zapotec Ruins.
ACCOM: Guesthouse - 2

Days 4-6 San Cristobal De Las Casas

Stay in a family run hotel and enjoy a boat trip down the Sumidero Canyon during a stay in the lovely San Cristobel de las Casas.
ACCOM: Hotel - 3

Day 7 Frontera Corozal

An early start and full day's drive take us to Frontera Corozal.
ACCOM: Camping (with facilities) - 1

Days 8-9 Palenque

Encounter the ancient Mayan city of Yaxchilan en route to Palenque, where the sight of this incredible, ruined city rising from the jungle is truly something to behold.
ACCOM: Camping (with facilities) - 2

Day 10 Merida

As the state capital of Yucatan, Merida boasts thriving markets and a bustling nightlife.
ACCOM: Hotel - 1

Days 11-12 Tulum

Reach the Caribbean Coast for some blissful camping on a remote beach near Xpu Ha. Then, venture to the alluring clifftop ruins of Maya-Toltec.
ACCOM: Camping (with facilities) - 2

Days 13-15 Caye Caulker

Wave goodbye to Mexico as a boat trip moves on to Caye Caulker in Belize. Relaxing to the max is compulsory on this idyllic Caribbean island.
ACCOM: Hotel - 3

Days 16-18 San Ignacio

Head to the Belize mainland, where there’s time to have a nosey around Belize City before moving on to San Ignacio – a beautiful town with lots of outdoor activities to enjoy or a place to simply relax.
ACCOM: Camping (with facilities) - 3

Day 19 Tikal

Drive across to Guatemala and be dumbstruck by the Mayan ruins of Tikal, with its temples hiding among the tropical jungle.
ACCOM: Camping (with facilities) - 1

Days 20-21 Poptun

Get to know what local life is like in Guatemala while spending time on a working farm in Poptun.
ACCOM: Camping (with facilities) - 2

Day 22 Rio Dulce

Soak up the unique Caribbean feel of the town and enjoy a splash in the local hot pools.
ACCOM: Hotel - 1

Days 23-26 Panajachel/Lake Atitlan/Chichicastenango

Soak up the atmosphere of Panajachel, which is situated on the shores of the beautiful Lake Atitlan. Perhaps embark on an optional boat trip around the lake that takes in the surrounding villages. The following day, visit Chichicastenango and its fantastic, multi-coloured market.
ACCOM: Camping (with facilities) - 3

Day 24 San Andres Itzapa

Jump aboard another boat and travel along the Rio Dulce to arrive in San Andres Itzapa where we spend the night at a community project assisting victims of domestic violence.
ACCOM: Guesthouse - 1

Days 27-28 Antigua

Appreciate the last couple of days in Guatemala by delving into the charms and wonder of Antigua.
ACCOM: Hotel - 1

Days 29-30 Los Cobanos

Ease into El Salvadorian life with a stay in the fishing village of Los Cobanos.
ACCOM: Camping (with facilities) - 2

Day 31 Cerro Verde National Park

Experience amazing views of surrounding volcanoes and countryside in Cerro Verde National Park.
ACCOM: Camping (with basic facilities) - 1

Day 32 Suchitoto

Wander the colourful streets of Suchitoto, which are lined cobblestone roads that lead to beautiful whitewashed houses.
ACCOM: Hotel - 1

Days 33-34 Copan

Get up close to the ancient ruins of Copan, one of Honduras’s most striking Mayan sites.
ACCOM: Camping (with facilities) - 2

Days 35-37 Roatan Island

Relax in the blissful, crystal-clear waters of Roatan Island, home to gorgeous beaches, intriguing mangroves and the Mesoamerican Barrier Reef, second in size only to Australia’s Great Barrier Reef.
ACCOM: Guesthouse - 3

Day 38 Lake Yojoa

Visit Lake Yojoa, where an overnight lakeside camp is the ideal opportunity to take in the surroundings.
ACCOM: Camping (with facilities) - 1

Days 39-40 Leon

Enter Nicaragua and head to the university town of Leon, peppered with derelict buildings and walls adorned with political murals and graffiti.
ACCOM: Hotel - 2

Days 41-42 Granada/Masaya National Park

Experience the wondrous crater and lava flows belonging to the active volcano in the heart of the Masaya National Park.
ACCOM: Camping (with basic facilities) - 1, Hotel - 1

Days 43-44 Ometepe Island

Cross Lake Nicaragua, Central America’s largest lake, to Isla Ometepe, where two volcanoes, lush vegetation and a wide range of wildlife await.
ACCOM: Hotel - 2

Days 45-46 La Fortuna/Arenal Volcano National Park

See Arenal Volcano and marvel at this beautiful area's majesty.
ACCOM: Camping (with facilities) - 2

Days 47-48 Monteverde

Stay within the rainforest at Costa Rica’s Monteverde, and perhaps witness some of the diverse local flora and fauna during a visit to the Cloud Forest Reserve.
ACCOM: Hotel - 2

Days 49-50 Manuel Antonio National Park

Sleep in cabins set within the jungle in Manuel Antonio National Park, embarking on jungle walks, relaxing on palm-lined beaches or swimming in cerulean waters.
ACCOM: Cabin - 2

Days 51-52 Boquete

Panama’s ‘wonderland’, Boquete, offers activities like rafting, hiking and volcano walks, as well as lush tropical forests.
ACCOM: Guesthouse - 2

Day 53 Santa Clara

An ideal opportunity to relax, swim in the lovely Pacific Ocean and camp by the beach before heading to Panama City.
ACCOM: Camping (with facilities) - 1

Days 54-55 Panama City

Visit the Panama Canal with enough time left to explore the city’s colourful neighbourhoods and soak up the last of the Central American atmosphere.
ACCOM: Hotel - 1